How COVID Threatens the Brain – With Dr. Frank Heppner | The Empowering Neurologist EP. 119

So how exactly does SARS-CoV-2 achieve the mind? This really is really a crucial question that we’ve significant solutions. Within this podcast, I’ve the recognition of interviewing Dr. Frank Heppner. His research uses electron microscopy to visualise intact coronavirus particles within the mind. Now that we know that COVID-19 isn’t just a respiratory system disease but could affect many other areas of the body such as the gastrointestinal system along with the central nervous system. One out of three people with COVID-19 does actually have nerve signs and symptoms and we will explore this of all time together today.

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Dr. Frank Heppner:

“Because of my lengthy-lasting expertise as trained physician and Professor for Neuropathology heading the Department of Neuropathology in the Charité – College Medicine Berlin, I’ve effectively were able to orchestrate top quality clinical work, although presenting novel concepts enabling economic success, largely by offering condition-of-the-art diagnostic plan to ~ 30 exterior hospitals and institutions. As I still positively conduct clinical-diagnostic operate in every area of neuropathology (neurooncology, neuroinflammation, neurodegeneration, neuromuscular illnesses, developmental disorders from the brain, CSF cytology), my research group aims to know the outcome from the defense mechanisms around the pathogenesis of nerve illnesses for example neurodegenerative illnesses, having an interdisciplinary systems medicine approach past the borders of compartments and, ultimately, disease entities. Generating and making use of murine disease models to be able to read the contribution of specific immune molecules within the pathogenesis of Alzheimer’s (AD) are my major research foci. For instance, we could reveal that inhibition from the immune molecules interleukin (IL)-12 and -23 produces a drastic amelioration of Alzheimer’s pathology. Besides, I’ve got a lengthy-standing curiosity about understanding microglia biology in health insurance and disease. To allow translation, I established a biobank to be able to collect tissues including brains from patients with neurodegenerative illnesses in addition to with COVID-19, which supported my translational efforts, recently inducing the identification of methods SARS-CoV-2 can go into the nervous system in people with COVID-19. In parallel, my Department has managed to become a world-leading research institution highlighted by substantial 3rd Party funding along with a constant record in excess of 150 peer-reviewed articles within the most esteemed scientific journals for example Science, Nature, Nature Medicine, and Nature Neuroscience among others, although effectively educating and promoting youthful guys which were employed to top institutions around the globe.”

He appears like quite a proficient individual, and again, we’re delighted to achieve the chance to spend more time with him.

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